Gα t2 (V34) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3874-50, BS3874-100

Sizes: 50µl, 100µl

Swiss-Prot: P19087

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC

Background: In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of Gα subunits have been identified; these include Gs, Gi, Gq and Gα 12/13. The Gi class comprises all the known α subunits that are susceptible to pertussis toxin modifications, including Gα i-1, Gα i-2, Gα i-3, Gα o, Gα t1, Gα t2, Gα z and Gα gust. In the well characterized visual system, photorhodopsin catalyzes the exchange of guanine nucleotides bound to the visual transducin Gα subunits (Gα t1 in rod cells and Gα t2 in cone cells).

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Gα t2 (V34) polyclonal antibody detects endogenous levels of Gα t2 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of Gα t2 (V34) pAb in paraffin-embedded human testis tissue.

Bioworld Molecular Weight: ~ 40 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: GGH; CONJUGASE; EC 3.4.19.9; GH; Folylpolygammaglutamyl Hydrolase; Gamma-Glu-X carboxypeptidase; gamma-glutamyl hydrolase; hGH

Immunogen: Synthetic peptide, corresponding to the N-terminus of Human Gα t2.

Conjugate: Unconjugated

Modification: Unmodified