CHRNA1 Polyclonal Antibody

Catalogue Numbers: BS62206-50, BS62206-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P02708

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Nicotinic acetylcholine receptors(AChRs) are found at the postsynaptic membrane of the neuromuscular junctionand bind acetylcholine molecules, allowing ions to move through thepore. Glutamate receptors are found in the postsynaptic membrane of cellsin the central nervous system. AChRα1, also known as ACHRD, CHRNA, CMS2A, FCCMS, SCCMS or CHRNA1, is a 482 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms, which are expressed in different tissues. Isoform 1 is only expressed in skeletal muscle whereas isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CHRNA1 polyclonal antibody detects endogenous levels of CHRNA1 protein.

Extra Notes: Western blot analysis of extracts of Jurkat cell line, using CHRNA1 polyclonal antibody.

Bioworld Molecular Weight: ~ 38 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Acetylcholine receptor subunit alpha; ACHRA; CHNRA; CHRNA1; ACHRD; CMS2A; FCCMS, SCCMS; Acra

Immunogen: Synthetic peptide, corresponding to Human CHRNA1.

Conjugate: Unconjugated

Modification: Unmodified