TSG-6 (V37) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2655-50, BS2655-100

Sizes: 50µl, 100µl

Swiss-Prot: P98066

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC, IF

Background: TSG6 is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is involved in extracellular matrix stability and cell migration. This protein forms a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhances the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. The expression of this gene can be induced by tumor necrosis factor alpha and interleukin-1. The expression can also be induced by mechanical stimuli in vascular smooth muscle cells, and is correlated with proteoglycan synthesis and aggregation.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TSG-6 (V37) polyclonal antibody detects endogenous levels of TSG-6 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of TSG-6 (V37) polyclonal antibody in extracts from MCF7 cells., Immunohistochemistry (IHC) analyzes of TSG-6 (V37) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.showing cytoplasmic staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Bioworld Molecular Weight: ~32 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: TNFAIP6; TNF-stimulated gene 6 protein; TSG6

Immunogen: Synthetic peptide, corresponding to the N-terminal of Human TSG-6.

Conjugate: Unconjugated

Modification: Unmodified