Casein Kinase Iγ2 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS71890-50, BS71890-100

Swiss-Prot: P78368

Host: Rabbit

Casein Kinase Iγ2 Polyclonal Antibody-BS71890

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC, IF

All Applications: WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Background: Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKIα, γ, ε and δ, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The α catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Casein Kinase Iγ2 polyclonal antibody detects endogenous levels of Casein Kinase Iγ2 protein.

Bioworld Molecular Weight: 47kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using CSNK1G2 antibody at 1:1000 dilution., Immunofluorescence analysis of A549 cell using CSNK1G2 antibody. Blue: DAPI for nuclear staining.

Alternative Name: Casein Kinase Iγ2; Casein kinase I isoform gamma-2; CKI-gamma 2; CSNK1G2; CK1G2; CKIγ2; CK-Iγ2; CKI-γ2; CKIγ-2; CKI γ2; CK Iγ2; CKI γ2; CKI γ 2; CKI gamma 2; CKI-gamma-2

Immunogen: Recombinant protein of human CSNK1G2

Modification: Unmodified

Conjugate: Unconjugated