J30-8 is a potent and isoform-selective inhibitor of c-Jun N-terminal kinase 3 (JNK3) with an IC50 of 40 nM, which 2500-fold isoform selectivity against JNK1α1 and JNK2α2. J30-8 exhibits neuroprotective activity in vitro and potential for the treatment of neurodegenerative diseases.

Product information

CAS Number: 2366255-71-0

Molecular Weight: 373.79

Formula: C17H9ClFN3O2S

Chemical Name: 3-{2-[(2-chlorophenyl)amino]-4-hydroxy-1,3-thiazol-5-yl}-5-fluoro-2H-indol-2-one

Smiles: OC1N=C(NC2=CC=CC=C2Cl)SC=1C1C(=O)N=C2C=CC(F)=CC2=1

InChiKey: BDCJVPSBCYWSSS-UHFFFAOYSA-N

InChi: InChI=1S/C17H9ClFN3O2S/c18-10-3-1-2-4-12(10)21-17-22-16(24)14(25-17)13-9-7-8(19)5-6-11(9)20-15(13)23/h1-7,24H,(H,21,22)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.