ACSL6 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS72377-50, BS72377-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9UKU0

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB 1:500 - 1:2000

Background: Acyl-CoA synthetases, also known as long-chain fatty-acid CoA synthases (FACL) or Palmitoyl-CoA ligases, include ACSL1-6, which are all single-pass membrane proteins localizing to the mitochondrion, microsome or peroxisome.ACSL proteins are important for synthesis of cellular lipids and for β-oxidation degradation. Specifically, ACSL proteins catalyze the activation of long-chain fatty acids to acyl-CoAs, which can be metabolized to form CO2, triacylglycerol (TAG), phospholipids (PL) and cholesteryl esters (CE). ACSL6 has been shown to be an Et V6 fusion partner gene in a recurrent t(5;12) (q31;p13) translocation in a patient with refractory anemia with excess blasts (RAEB) with basophilia, a patient with acute myelogenous leukemia (AML) with eosinophilia, and a patient with acute eosinophilic leukemia (AEL).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ACSL6 polyclonal antibody detects endogenous levels of ACSL6 protein.

Bioworld Molecular Weight: ~ 78 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of various cell lines, using ACSL6 antibody.

Alternative Name: Long-chain-fatty-acid--CoA ligase 6; Long-chain acyl-CoA synthetase 6; LACS 6; ACSL6; ACS2; FACL6; KIAA0837; LACS5

Immunogen: Recombinant protein of human ACSL6

Conjugate: Unconjugated

Modification: Unmodified