Phospho-PKR (Thr451) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11432-50, MB11432-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P19525

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: PKR a protein kinase of the PEK family. Upon binding double-stranded RNA, it becomes autophosphorylated and activated. Phosphorylates and inhibits the alpha subunit of eIF2 alpha, which leads to an inhibition of the initiation of protein synthesis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PKR in Hela, Hela+CalyculinALysates using Phospho-PKR antibody.

Bioworld Molecular Weight: Calculated MW: 62 kDa; Observed MW: 74 kDa

Specificity: IgG

Alternative Name: EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Thr451 of human PKR

Conjugate: Unconjugated

Modification: Phosphorylated