LT-β rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8728-50, ES8728-100

Citations, Manuals and MSDS Available upon request.

Background: Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Alternate Name: Lymphotoxin-beta (LT-beta; Tumor necrosis factor C; TNF-C; Tumor necrosis factor ligand superfamily member 3)

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: IHC-p 1:50-200, ELISA 1:10000-20000, WB 1:500-2000

Reactivity: Human; Rat; Mouse;

Immunogen: Synthetic peptide from human protein at AA range: 41-90

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 4050

Human SWISS Prot NO: Q06643

Subcellular Location: Membrane; Single-pass type II membrane protein.

Research Use Only