TNF α Rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: EA251-50, EA251-100

Citations, Manuals and MSDS Available upon request.

Background: TNF-α, the prototypical member of the TNF protein superfamily, is a homotrimeric type-II membrane protein. It can cause cytolysis of certain tumor cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, causing fever by direct action or by stimulation of  interlerukin-1 secretion; it can stimulate cell proliferation and induce cell differentiation under certain conditions.

Alternate Name: APC1 antibody, DIF antibody, TNFSF2 antibody, Tumor necrosis factor alpha antibody

Source: Rabbit

Applications: WB, IHC

Dilution: WB 1:1, 000-2, 000  IHC 1:100-200

Reactivity: Human, Rat, Mouse

Immunogen: Recombinant Protein

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality: Polyclonal

Isotype: IgG

Concentration: 1mg/mL

Observed Band (KD): 17, 25kDa

Human Gene ID: 7124

Human SWISS Prot NO: P01375

Subcellular Location: Secreted, Cell membrane

Research Use Only