FAST rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES2328-50, ES2328-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008],

Alternate Name: FASTK; Fas-activated serine/threonine kinase; FAST kinase

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human FAST. AA range:361-410

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 61kD

Human Gene ID: 10922

Human SWISS Prot NO: Q14296

Subcellular Location: [Isoform 4]: Mitochondrion matrix. Colocalizes with mitochondrial RNA granules.

Research Use Only