MUSK rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20265-50, ES20265-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Oct 2009],

Alternate Name: Muscle, skeletal receptor tyrosine-protein kinase (EC 2.7.10.1; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor)

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human MUSK

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 4593

Human SWISS Prot NO: O15146

Subcellular Location: Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein. Colocalizes with acetylcholine receptors (AChR) to the postsynaptic cell membrane of the neuromuscular junction.

Research Use Only