GLS Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-53314-60, E-AB-53314-120, E-AB-53314-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GLS

Target Synonym: AAD20; DKFZp686O15119; FLJ10358; GAC; GAM; GLS; GLS1; GLSK; Glutaminase C; Glutaminase kidney isoform; Glutaminase phosphate activated; K-glutaminase; KGA; KIAA0838; L-glutamine amidohydrolase; mitochondrial

Research Areas: Cancer, Metabolism, Neuroscience, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O94925

Background: GLS, also named as GLS1 and KIAA0838, belongs to the glutaminase family. It catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Glutaminase-, glutamate-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease.The glutaminase band in AA/C1 cells is more intense than in HT29 cells, in accordance with measurements of glutaminase activity, and had the same molecular mass of approx. 63 kDa. The bands for both cell lines are clearly different in size from both rat liver glutaminase (58 kDa) and rat kidney glutaminase (65 kDa). It also reveals a molecular weight of 83-84 kDa as a phosphate-dependent glutaminase. It has 3 isoforms named as KGA, GAM, GAC.

Concentration: 0.78 mg/mL

Immunogen: Synthetic peptide of human GLS

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:100, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only