Recombinant Human HABP2 Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH033464-10, PKSH033464-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: HABP2

Target Symptom: Hyaluronan-binding protein 2; Factor VII-activating protease; Factor seven-activating protease; Hepatocyte growth factor activator-like protein; Plasma hyaluronan-binding protein

Research Area: Cardiovascular

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-6His

UNIProt ID: Q14520

Accession: Q14520

Background: Hyaluronan-binding protein 2（HABP2） is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator to the active two chain form, activates coagulation factor VII.

Sequence: Met1-Gln279

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 36.2 kDa

Observed MW: 38 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only