OATP-C rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4514-50, ES4514-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009],

Alternate Name: SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6; Solute carrier organic anion transporter family member 1B1; Liver-specific organic anion transporter 1; LST-1; OATP-C; Sodium-independent organic anion-transporting polypeptide 2; OATP-2; Solut

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human SLCO1B1. AA range:251-300

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 76kD

Human Gene ID: 10599

Human SWISS Prot NO: Q9Y6L6

Subcellular Location: Basolateral cell membrane; Multi-pass membrane protein. Detected in basolateral membranes of hepatocytes.

Research Use Only