NLRP12 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-66298-60, E-AB-66298-120, E-AB-66298-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NLRP12

Target Synonym: NLRP12; CLR19.3; FCAS2; NALP12; PAN6; PYPAF7; RNO; RNO2

Research Areas: Cell Biology, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P59046

Background: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human NLRP12 (NP_001264055.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 31kDa/101kDa/107kDa/113kDa/114kDa/120kDa

Observed MW: 120kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only