Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.

Product information

CAS Number: 57-67-0

Molecular Weight: 214.24

Formula: C7H10N4O2S

Chemical Name: N''-(4-aminobenzenesulfonyl)guanidine

Smiles: NC(N)=NS(=O)(=O)C1C=CC(N)=CC=1

InChiKey: BRBKOPJOKNSWSG-UHFFFAOYSA-N

InChi: InChI=1S/C7H10N4O2S/c8-5-1-3-6(4-2-5)14(12,13)11-7(9)10/h1-4H,8H2,(H4,9,10,11)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (466.77 mM; Need ultrasonic). H2O : 3.33 mg/mL (15.54 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Sulfaguanidine (2.5 mg/kg; i.v.) exhibits CLt (adult 0.29, neonate 0.14 L/h/kg), AUC0-∞ (adult 8.18, neonate 20.46 μg•h/mL), and Vdss (adult 0.65, neonate 0.59 L/kg) in rats. Sulfaguanidine (2.5 mg/kg; p.o.) exhibits absolute bioavailability (adult 12.76%, neonate 57.86%), Cmax (adult 0.41, neonate 3.56 μg/mL), and Tmax (adult 1.67, neonate 1.50 h) in rats.

Products are for research use only. Not for human use.