ERK1/2 (4F3) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3095-50, MB3095-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P27361/P28482

Host: Mouse

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of ERK1/2 in Jurkat, A549, C6, 3T3 and HelaLysates using p44/42 MAPK antibody.

Bioworld Molecular Weight: Calculated MW: 44,42 kDa; Observed MW: 42,44 kDa

Specificity: IgG1

Alternative Name: MAPK3; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; MAPK1; ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK.

Immunogen: Human p44 MAPK (Erk1) synthetic peptide conjugated to KLH.

Conjugate: Unconjugated

Modification: Unmodified