ELOVL1 (F139) Polyclonal Antibody

Catalogue Numbers: BS3121-50, BS3121-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9BW60

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 1 (ELOVL1), also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in a variety of tissues and at especially high levels in stomach, skin, intestine, kidney and lung. ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids of up to 26 carbons and may be required for the development of a barrier in epithelial cells and skin. ELOVL1 is also important for the formation of Myelin in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ELOVL1 (F139) polyclonal antibody detects endogenous levels of ELOVL1 protein.

Extra Notes: Western blot (WB) analysis of ELOVL1 (F139) pAb at 1:500 dilution
Lane1:MCF-7 whole cell lysate(40ug)
Lane2:HEK293T whole cell lysate(40ug)
Lane3:Hela whole cell lysate(40ug)
Lane4:The Kidney tissue lysate of Mouse(40ug)
Lane5:The Kidney tissue lysate of Rat(40ug)

Bioworld Molecular Weight: ~ 45 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Elongation of very long chain fatty acids protein 1; 3-keto acyl-CoA synthase ELOVL1; ELOVL fatty acid elongase 1; ELOVL FA elongase 1; Very-long-chain 3-oxoacyl-CoA synthase 1; CGI-88; CGI88; SSC1; ELOVL1

Immunogen: Synthetic peptide, corresponding to amino acids 104-156 of Human ELOVL1.

Conjugate: Unconjugated

Modification: Unmodified