Hairless (E77) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS9123-50, BS9123-100

Sizes: 50µl, 100µl

Swiss-Prot: O43593

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

Background: Drosophila genes can be categorized based on the type of protein for which they encode and are represented by six major classifications, which include intracellular signaling proteins, transmembrane proteins, RNA binding proteins, secreted factors, transcription regulators (basic helix-loop-helix, homeodomain containing, zinc finger containing and chromatin associated) or other functional proteins. Among these numerous proteins, Hairless (CG5460, CT36411, CT17282) is a transcriptional co-repressor that contains a “Paired box” domain, a KX-repeat domain, a NEDL-repeat domain and a serine-rich domain. Hairless is an antagonist of the Notch signaling pathway in Drosophila.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Hairless (E77) polyclonal antibody detects endogenous levels of Hairless protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of HR pAb at 1:500 dilution
Lane 1: The Small intestine tissue lysate of Rat (40ug)
Lane 2: A375 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of Hairless (E77) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 127 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Lysine-specific demethylase hairless; HR; CG5460; CT36411; CT17282

Immunogen: Synthetic peptide, corresponding to amino acids 51-100 of Human Hairless.

Conjugate: Unconjugated

Modification: Unmodified