SOX9 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91275-50, BS91275-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P48436(Human) Q04887(Mouse) Unigene:95086(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IHC, IP, , FC

All Applications: WB:1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: SOX9 polyclonal antibody detects endogenous levels of SOX9 protein.

Bioworld Molecular Weight: 56 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining SOX9 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining SOX9 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: SOX9, campomelic dysplasia autosomal sex reversal, CMD 1, CMD1, CMPD 1, CMPD1, SOX 9, Sox9, SOX9, SRA 1, SRA1, SRXX2, SRXY10, SRY (sex determining region Y) box 9 (campomelic dysplasia autosomal, SRY (sex determining region Y) box 9, SRY (sex determining region Y)-box 9, SRY (sex-determining region Y)-box 9 protein, SRY related HMG box gene 9, Transcription factor SOX 9, Transcription factor SOX-9, transcription factor SOX9,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified