Troponin I-FS Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA12115-50, RA12115-100

Citations, Manuals and MSDS Available upon request.

Background: troponin I2, fast skeletal type (TNNI2) Homo sapiens This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced trans

Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF (paraffin section) ; FCM; ELISA

Species Cross-Reactivity: Human

GeneID (Human): 7136

SWISS: P48788

Source: Mouse

Research Use Only