PIN1 Monoclonal Antibody

Catalogue Numbers: MB67093-50, MB67093-100

Sizes: 50µl, 100µl

Product: Mouse IgG1. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: Q13526

Host: Mouse

Reactivity: Human, Mouse, Rat, Monkey

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Pin1, a member of the parvulin family of peptidyl-prolyl isomerases (PPIase), has been implicated in the G2/M transition of the mammalian cell cycle. Pin1 is a small (18 kDa) protein with two distinct functional domains: an amino-terminal WW domain and a carboxy-terminal PPlase domain. Pin1 interacts with several mitotic phosphoproteins, including Plk1, cdc25C and cdc27, and is thought to act as a phosphorylation-dependent PPlase for these target molecules.

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of PIN1 protein.

Extra Notes: Western blot analysis of PIN1 expression in K562 (A), Hela (B), 293 (C) whole cell lysates.

Bioworld Molecular Weight: ~ 18 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; Rotamase Pin1

Immunogen: Recombinant fusion protein of human PIN1. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified