Mcl1-IN-3 is an inhibitor of Mcl1 extracted from patent WO2015153959A2, compound example 57; has an IC50 and Ki of 0.67 and 0.13 μM, respectively.

Product information

CAS Number: 1814891-79-6

Molecular Weight: 487.93

Formula: C27H22ClN3O4

Chemical Name: 1-{[4-(4-chloro-3,5-dimethylphenoxy)phenyl]methyl}-6-(furan-2-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

Smiles: CC1C=C(C=C(C)C=1Cl)OC1C=CC(CN2N=C(C)C3=C2N=C(C=C3C(O)=O)C2=CC=CO2)=CC=1

InChiKey: LTAWGVCXLNOXJX-UHFFFAOYSA-N

InChi: InChI=1S/C27H22ClN3O4/c1-15-11-20(12-16(2)25(15)28)35-19-8-6-18(7-9-19)14-31-26-24(17(3)30-31)21(27(32)33)13-22(29-26)23-5-4-10-34-23/h4-13H,14H2,1-3H3,(H,32,33)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.