ZnT-8 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36639-50, RA36639-100

Citations, Manuals and MSDS Available upon request.

Background: solute carrier family 30 member 8 (SLC30A8) Homo sapiens The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM) . Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 169026

Protein MW (KDa): 41

SWISS: Q8IWU4

Source: Rabbit

Research Use Only