Flt-4 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8649-50, ES8649-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008],

Alternate Name: Vascular endothelial growth factor receptor 3 (VEGFR-3; EC 2.7.10.1; Fms-like tyrosine kinase 4; FLT-4; Tyrosine-protein kinase receptor FLT4)

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthetic peptide from human protein at AA range: 640-700

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 170kD

Human Gene ID: 2324

Human SWISS Prot NO: P35916

Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Nucleus. Ligand-mediated autophosphorylation leads to rapid internalization.; [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Ligand-mediated autophosphorylation leads to rapid internalization.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted. Cytoplasm.

Research Use Only