Fgl2 (V38) Polyclonal Antibody

Catalogue Numbers: BS2972-50, BS2972-100

Sizes: 50µl, 100µl

Alternative Name: Fibroleukin; Fibrinogen-like protein 2; pT49; FGL2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q14314

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role,such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively xpressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation.
Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Fgl2 (V38) polyclonal antibody detects endogenous levels of Fgl2 protein.

Bioworld Molecular Weight: ~ 50 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Fgl2 (V38) pAb at 1:500 dilution
Lane 1: CT26 whole cell lysate(40ug)
Lane 2: SP2/0 whole cell lysate(40ug)
Lane 3: C6 whole cell lysate(40ug)
Lane 4: A549 whole cell lysate(40ug)
Lane 5: Hela whole cell lysate(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 6-60 of Human Fgl2.

Conjugate: Unconjugated

Modification: Unmodified