TAT (E304) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3522-50, BS3522-100

Sizes: 50µl, 100µl

Swiss-Prot: P17735

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

Background: TAT (tyrosine aminotransferase) is a 454 amino acid protein that localizes to mitochondria and belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Existing as a homodimer, TAT uses pyridoxal phosphate as a cofactor to catalyze the conversion of L-tyrosine into p-hydroxyphenylpyruvate, a reaction that is important in amino acid degradation. Defects in the gene encoding TAT are the cause of tyrosinemia type 2 (TYRO2), an inborn error of metabolism that is associated with elevated levels of tyrosine in blood and urine and is characterized by palmoplantar keratosis, painful corneal ulcers and mental retardation. The gene encoding TAT maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: TAT (E304) polyclonal antibody detects endogenous levels of TAT protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of TAT (E304) pAb in paraffin-embedded human breast carcinoma tissue.

Bioworld Molecular Weight: ~ 51 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Tyrosine aminotransferase; TAT; L-tyrosine:2-oxoglutarate aminotransferase

Immunogen: Synthetic peptide, corresponding to amino acids 270-320 of Human TAT.

Conjugate: Unconjugated

Modification: Unmodified