Na+/K+-ATPase α2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27574-50, RA27574-100

Citations, Manuals and MSDS Available upon request.

Background: ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2) Homo sapiens The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta) . The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: ATP1A2; KIAA0778; Sodium/potassium-transporting ATPase subunit alpha-2; Na (+) /K (+) ATPase alpha-2 subunit; Sodium pump subunit alpha-2

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse; Rat; Monkey

GeneID (Human): 477

Protein MW (KDa): 112

SWISS: P50993

Source: Rabbit

Research Use Only