L-R4W2 is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1), with an IC50 of 0.1 μM. L-R4W2 may act as a potent analgesic.

Product information

CAS Number: 206350-79-0

Molecular Weight: 1014.19

Formula: C46H71N21O6

Chemical Name: (Z,2S)-2-[(Z)-[(2S)-2-[(Z)-[(2S)-2-[(Z)-[(2S)-2-amino-5-carbamimidamido-1-hydroxypentylidene]amino]-5-carbamimidamido-1-hydroxypentylidene]amino]-5-carbamimidamido-1-hydroxypentylidene]amino]-5-carbamimidamido-N-[(1S)-1-[(Z)-[(1S)-1-(C-hydroxycarbonimidoyl)-2-(1H-indol-3-yl)ethyl]-C-hydroxycarbonimidoyl]-2-(1H-indol-3-yl)ethyl]pentanimidic acid

Smiles: N[C@@H](CCCNC(N)=N)/C(/O)=N/[C@@H](CCCNC(N)=N)/C(/O)=N/[C@@H](CCCNC(N)=N)/C(/O)=N/[C@@H](CCCNC(N)=N)/C(/O)=N/[C@@H](CC1=CNC2=CC=CC=C12)/C(/O)=N/[C@@H](CC1=CNC2=CC=CC=C12)C(=N)O

InChiKey: MGQHBRDQUJRCLN-UJARKJSPSA-N

InChi: InChI=1S/C46H71N21O6/c47-29(11-5-17-57-43(49)50)38(69)63-32(14-6-18-58-44(51)52)39(70)64-33(15-7-19-59-45(53)54)40(71)65-34(16-8-20-60-46(55)56)41(72)67-36(22-26-24-62-31-13-4-2-10-28(26)31)42(73)66-35(37(48)68)21-25-23-61-30-12-3-1-9-27(25)30/h1-4,9-10,12-13,23-24,29,32-36,61-62H,5-8,11,14-22,47H2,(H2,48,68)(H,63,69)(H,64,70)(H,65,71)(H,66,73)(H,67,72)(H4,49,50,57)(H4,51,52,58)(H4,53,54,59)(H4,55,56,60)/t29-,32-,33-,34-,35-,36-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.