APC Anti-Mouse IL-10 Antibody [JES5-16E3]

Size: 100μg

Catalogue Number: E-AB-F1197UE-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: IL-10

Target Synonym: Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF,

Conjugation: APC

Host: Rat

Species Reactivity: Mouse

Application: ICFCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Rat IgG2b, κ

Clone No.: JES5-16E3

UNIProt ID: P18893

Background: L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones, inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis, suppresses the delayed type hypersensitivity response, stimulates Th2 cell response (which results in elevated antibody production), and promotes mast cell proliferation in combination with IL-4.

Concentration: 0.2 mg/mL

Control Catalogue Number: E-AB-F09843E

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 16153

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag