GDF7 Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Catalogue Numbers: BS65262-50, BS65262-100

Sizes: 50µl, 100µl

Swiss-Prot: Q7Z4P5

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,IHC-p,If (paraffin section),ELISA

Background: growth differentiation factor 7(GDF7) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016]

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: GDF-7 Polyclonal Antibody detects endogenous levels of GDF-7 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of Hela cells using GDF-7 Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody (catalog#：RS0002) was diluted at 1:20000, Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200

Bioworld Molecular Weight: ~ 47 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: GDF7; Growth/differentiation factor 7; GDF-7

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GDF7. AA range:321-370

Conjugate: Unconjugated

Modification: Unmodified