Ubiquilin 3 Polyclonal Antibody

Catalogue Numbers: BS62507-50, BS62507-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9H347

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, IHC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200

Background: Ubiquitin (Ub) is among the most phylogenetically conserved proteins known. The primary function of this small, 76 amino acid protein is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S proteosome. Many ubiquitin-like proteins function as post-translational protein modifiers, such as members of the SUMO protein family, however some ubiquitin-like proteins regulate protein-protein interactions and cell cycle events, thereby functioning outside of the traditional ubiquitination pathway. UBQLN3 (Ubiquilin-3) is a 654 amino acid protein containing one N-terminal ubiquitin-like (UBQ) domain and one C-terminal UBA domain. With expression limited to testis, it has been suggested that UBQLN3 may associate with testis-specific cyclin A1 and/or cyclin A to regulate the cell cycle during spermatogenesis. Similarly, a family member related to UBQLN3, namely PLIC-1, also known as Ubiquilin-1, may also play a critical role in cell cycle regulation.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Ubiquilin 3 polyclonal antibody detects endogenous levels of Ubiquilin 3 protein.

Extra Notes: Western blot (WB) analysis of Ubiquilin 3 polyclonal antibody at 1:500 dilution
LaneA:A549 whole cell lysate

Bioworld Molecular Weight: ~ 71 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Ubiquilin-3; UBQLN3

Immunogen: Synthetic peptide, corresponding to Human Ubiquilin 3.

Conjugate: Unconjugated

Modification: Unmodified