ZAP70 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11797-50, MB11797-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P43403

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of ZAP70 in JurkatLysates using ZAP70 antibody.

Bioworld Molecular Weight: Calculated MW: 70 kDa; Observed MW: 70 kDa

Specificity: IgG

Alternative Name: ZAP70; SRK; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase

Immunogen: A synthetic peptide of human ZAP70

Conjugate: Unconjugated

Modification: Unmodified