SOX8 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65695-50, BS65695-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: P57073

Host: Rabbit

Reactivity: Human, Mouse, Rat,Cow, Horse,

Applications: IHC-P

All Applications: IHC-P=1:100-500

Background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: SOX8 Polyclonal Antibody detects endogenous levels of SOX8 protein.

Bioworld Molecular Weight: 47 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes;Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (SOX8) Polyclonal Antibody, Unconjugated (bs-11600R) at 1:400 overnight at 4°C

Alternative Name: SOX 8; Sox8; SOX8_HUMAN; SRY (sex determining region Y) box 8; SRY box 8; SRY box containing gene 8; Transcription factor SOX 8; Transcription factor SOX-8; Transcription factor SOX8.

Immunogen: KLH conjugated synthetic peptide derived from human SOX8

Conjugate: Unconjugated

Modification: Unmodified