Coilin Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90316-50, BS90316-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P38432(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, FC

All Applications: WB:1:500-1:2,000
FC:1:50-1:100

Background: Coilin protein is one of the main molecular components of Cajal bodies (CBs). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. In addition to its structural role, coilin acts as glue to connect the CB to the nucleolus. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome and chromosome.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Coilin polyclonal antibody detects endogenous levels of Coilin protein.

Bioworld Molecular Weight: 63 kDa (Predicted band size)

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Coilin on rat kidney tissue lysates using anti-Coilin at 1/500 dilution., Flow cytometric analysis of Jurkat cells with Coilin antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.

Alternative Name: COIL, CLN80, CLN 80, CLN80, COIL, COIL, Coilin, Coilin p80, p80, P80 coilin,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified