Chlorquinaldol is an antimicrobial agent used for local antisepsy.

Product information

CAS Number: 72-80-0

Molecular Weight: 228.07

Formula: C10H7Cl2NO

Synonym:

Chloquinan

Chemical Name: 5,7-dichloro-2-methylquinolin-8-ol

Smiles: CC1C=CC2=C(N=1)C(O)=C(Cl)C=C2Cl

InChiKey: GPTXWRGISTZRIO-UHFFFAOYSA-N

InChi: InChI=1S/C10H7Cl2NO/c1-5-2-3-6-7(11)4-8(12)10(14)9(6)13-5/h2-4,14H,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C). 46 mg/mL(201.69 mM). Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Chlorquinaldol is a derivative of hydroxy-8-quinolein. For 0.1 to 0.2% (W/V) chlorquinaldol concentrations, a reduction of about 104 organisms is obtained after 60 minutes for N. gonorrhoeae and C. trachomatis. However, for technical problems, the concentrations tested are 10 to 100 times lower than the doses usually recommended for this antiseptic. Chlorquinaldol displays enhanced bactericidal activity in duodeno-pancreatic secretions.

References:

1. Bortolin M, et al. In vitro Antimicrobial Activity of Chlorquinaldol against Microorganisms Responsible for Skin and Soft Tissue Infections: Comparative Evaluation with Gentamicin and Fusidic Acid. Front Microbiol. 2017 Jun 8;8:1039.

Products are for research use only. Not for human use.