STAR Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-15419-60, E-AB-15419-120, E-AB-15419-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: STAR

Target Synonym: Cholesterol trafficker; Luteinizing hormone induced protein; mitochondrial; Mitochondrial steroid acute regulatory protein; StAR; StAR related lipid transfer (START) domain containing 1; STAR; StARD1; START domain containing 1; START domain containing protein 1; START domain-containing protein 1; Steroid acute regulatory protein; Steroidogenic acute regulator; Steroidogenic acute regulatory protein; Steroidogenic acute regulatory protein mitochondrial

Research Areas: Cancer, Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P49675

Background: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13.

Concentration: 0.6 mg/mL

Immunogen: Recombinant protein of human STAR

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000, IHC 1:25-1:100

Calculated MW: 32kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only