ENO1 (3F7) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3097-50, MB3097-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P06733

Host: Mouse

Reactivity: Human, Mouse, Rat,Monkey

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.MiscellaneousUsed as a diagnostic marker for many tumors and, in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest. Also marker for endometriosis. Antibodies against alpha-enolase are present in sera from patients with cancer-associated retinopathy syndrome (CAR), a progressive blinding disease which occurs in the presence of systemic tumor growth, primarily small-cell carcinoma of the lung and other malignancies. Is identified as an autoantigen in Hashimoto encephalopathy (HE) a rare autoimmune disease associated with Hashimoto thyroiditis (HT). HT is a disorder in which destructive processes overcome the potential capacity of thyroid replacement leading to hypothyroidism.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Enolase1 in T47D, 3T3, COS7, C6 and HelaLysates using Enolase1 antibody.

Bioworld Molecular Weight: Calculated MW: 47 kDa; Observed MW: 47 kDa

Specificity: IgG1

Alternative Name: NNE; PPH; MPB1; ENO1L1; HEL-S-17

Immunogen: Purified recombinant human Enolase-1 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified