Recombinant Human MMP-9 protein (His tag)

Sizes: 20μg, 100μg

Catalogue Numbers: PDMH100118-20, PDMH100118-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: MMP-9

Target Synonym: Matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; Gelatinase B; MMP9; CLG4B; GELB; MANDP2

UNIProt ID: P14780

Research Areas: Signal Transduction; Cell biology; Cardiovascular; Cancer;

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-His

Accession: P14780

Background: Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein; which is produced by normal alveolar macrophages and granulocytes; can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4; SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; angiogenesis; bone development; wound healing; cell migration; learning and memory; as well as in pathological processes; such as arthritis; intracerebral hemorrhage; and metastasis.

Sequence: Met 1-Asp 707

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: Please contact us for more information.

Calculated MW: 77.66 kDa

Observed MW: 85 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only