DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 663599-10-8

Molecular Weight: 411.50

Formula: C17H21N3O5S2

Chemical Name: 2,5-dioxopyrrolidin-1-yl 4-{[3-(dimethylcarbamoyl)pyridin-4-yl]disulfanyl}pentanoate

Smiles: CN(C)C(=O)C1=CN=CC=C1SSC(C)CCC(=O)ON1C(=O)CCC1=O

InChiKey: AFGUQHOCEUTKEQ-UHFFFAOYSA-N

InChi: InChI=1S/C17H21N3O5S2/c1-11(4-7-16(23)25-20-14(21)5-6-15(20)22)26-27-13-8-9-18-10-12(13)17(24)19(2)3/h8-11H,4-7H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Products are for research use only. Not for human use.