Csk (L558) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS1739-50, BS1739-100

Sizes: 50µl, 100µl

Swiss-Prot: P41240

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein).

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Csk (L558) polyclonal antibody detects endogenous levels of Csk protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Csk (L558) pAb at 1:500 dilution
Lane 1: PMVEC whole cell lysate (20ug)
Lane 2: AML-12 whole cell lysate (40ug)
Lane 3: H1792 whole cell lysate (40ug)
Lane 4: HepG2 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of Csk (L558) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 50 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL; CSK

Immunogen: Synthetic peptide, corresponding to amino acids C-terminus of Human Csk.

Conjugate: Unconjugated

Modification: Unmodified