Gas6 (G309) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2563-50, BS2563-100

Sizes: 50µl, 100µl

Swiss-Prot: Q14393

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Gas6 (G309) polyclonal antibody detects endogenous levels of Gas6 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Gas6 (G309) polyclonal antibody at 1:500 dilution
Lane 1: MCF-7 whole cell lysate
Lane 2: Mouse heart tissue lysate
Lane 3: PC12 whole cell lysate, Immunohistochemistry (IHC) analyzes of Gas6 (G309) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 80 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Growth arrest-specific protein 6; GAS-6; AXL receptor tyrosine kinase ligand; AXLLG; GAS6

Immunogen: Synthetic peptide, corresponding to amino acids 278-328 of Human Gas6.

Conjugate: Unconjugated

Modification: Unmodified