PE/Cyanine5 Anti-Rat CD44H Antibody [OX-49]

Size: 100μg

Catalogue Number: E-AB-F1225UG-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD44H

Target Synonym: Pgp-1, H-CAM, CD44s, CD44H,

Conjugation: PE/Cyanine5

Host: Mouse

Species Reactivity: Rat

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Mouse IgG2a, κ

Clone No.: OX-49

UNIProt ID: P26051

Background: CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

Concentration: 0.2 mg/mL

Control Catalogue Number: E-AB-F09803G

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 12505

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag