FITC Anti-Mouse CD117/c-Kit Antibody [2B8]

Size: 100μg

Catalogue Number: E-AB-F1092UC-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD117/c-Kit

Target Synonym: Mast/stem cell growth factor receptor Kit, Kit, SCFR, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, CD117,

Conjugation: FITC

Host: Rat

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Rat IgG2b, κ

Clone No.: 2B8

UNIProt ID: P05532

Background: CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F09843C

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 16590

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag