p19 INK4d Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70351-60, E-AB-70351-120, E-AB-70351-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: p19 INK4d

Target Synonym: CDK inhibitor p19INK4d; CDKN2D; Cyclin dependent kinase inhibitor 2D; Cyclin-dependent kinase 4 inhibitor D; Cyclin-dependent kinase inhibitor 2D (p19; inhibits CDK4); inhibitor of cyclin-dependent kinase 4d; INK4D; MGC109660; MGC137547; MGC73010; p19; p19-INK4D; p19INK4d; Similar to cyclin-dependent kinase inhibitor 2D

Research Areas: Cancer,Cell Biology,Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P55273,Q60773

Background: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Concentration: 2.6 mg/mL

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse p19 INK4d

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 19kDa

Observed MW: 19kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only