Acetyl-p53 (Lys370) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16614-50, BZ16614-100

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Swiss-Prot: P04637

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,ICC/IF,IP

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of p53 in HeLaLysates treated with Trichostatin A using Acetyl-p53 antibody.

Bioworld Molecular Weight: Calculated MW: 44 kDa; Observed MW: 53 kDa

Specificity: IgG

Alternative Name: Antigen NY-CO-13; Cellular tumor antigen p53; Phosphoprotein p53; TP53; Tumor suppressor p53

Immunogen: A synthesized peptide derived from human p53 (acetyl K370)

Conjugate: Unconjugated

Modification: Acetylated