PCNA Monoclonal Antibody (12D10), HRP Conjugated

Size: 50μL, 100μL

Catalogue Numbers: RA11821-50, RA11821-100

Citations, Manuals and MSDS Available upon request.

Background: proliferating cell nuclear antigen (PCNA) Homo sapiens The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.

Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Applications: WB; IF/ICC; IHC-p

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 5111

SWISS: P12004

Source: Mouse

Research Use Only