EAF2 Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS8722-50, BS8722-100

Swiss-Prot: Q96CJ1

Host: Rabbit

EAF2 Polyclonal Antibody-BS8722

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IF

All Applications: WB: 1:500~1:2000
IF: 1:50~1:200

Background: EAF1 and EAF2 can form a complex with ELL that targets the ternary elongation complex of Pol II, stimulating the rate of elongation. In addition, EAF1 and EAF2 are important for the stability of the NuA4 histone acetyltransferase complex, which transcriptionally activates certain genes by acetylation of Histones H4 and H2A. Both EAF1 and EAF2 are ubiquitously expressed members of the EAF family that colocalize with ELL to the the Cajal bodies and nuclear speckles. EAF1 contains a C-terminal region rich in aspartic acid, glutamic acid and serine residues. EAF2 is an androgen-response gene and can act as a potent apoptosis inducer.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: EAF2 polyclonal antibody detects endogenous levels of EAF2 protein.

Bioworld Molecular Weight: ~ 35 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using EAF2 antibody., Immunofluorescence analysis of A549 cell using EAF2 antibody. Blue: DAPI for nuclear staining.

Alternative Name: ELL-associated factor 2; Testosterone-regulated apoptosis inducer and tumor suppressor protein; EAF2; TRAITS; BM-040

Immunogen: Recombinant full length Human EAF2.

Modification: Unmodified

Conjugate: Unconjugated