APOA1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90075-50, BS90075-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P02647(Human) Q00623(Mouse)

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, ICC/IF, IHC, IP,

All Applications: WB:1:1,000
ICC:1:50-1:200
IHC:1:50-1:200

Background: Apolipoproteins are protein components of plasma lipoproteins. The human apoA-I gene encodes a single chain, 243 amino acid protein which promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. It can function as a cofactor for lecithin cholesterolacyltransferase (LCAT), which is responsible for the formation of most plasma cholesteryl esters. The human apoA-II gene encodes the second most abundant protein of HDL particles, where it influences plasma levels of free fatty acids (FFA). The human apoA-IV gene encodes a 396 amino acid preprotein, which after proteolytic processing is secreted from the intestine in association with chylomicron particles. ApoA-IV is a potent activator of LCAT in vitro. The human apoA-V gene encodes a 366 amino acid protein that is believed to be an important determinant of plasma triglyceride levels.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: APOA1 polyclonal antibody detects endogenous levels of APOA1 protein.

Bioworld Molecular Weight: 31 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining Apolipoprotein A1 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining Apolipoprotein A1 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: Apo-AI, ApoA-I, APOA1, Apo-AI, ApoA I, ApoA-I, APOA1, APOA1, Apolipoprotein A-I(1-242), Apolipoprotein A1, Apolipoprotein AI, Brp14, Ltw1, Lvtw1, Sep1, Sep2,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified