(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. (2R,4R)-APDC has anticonvulsant and neuroprotective effects.

Product information

CAS Number: 169209-63-6

Molecular Weight: 174.15

Formula: C6H10N2O4

Chemical Name: (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid

Smiles: N[C@]1(CN[C@H](C1)C(O)=O)C(O)=O

InChiKey: XZFMJVJDSYRWDQ-AWFVSMACSA-N

InChi: InChI=1S/C6H10N2O4/c7-6(5(11)12)1-3(4(9)10)8-2-6/h3,8H,1-2,7H2,(H,9,10)(H,11,12)/t3-,6-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

2R, 4R-APDC (1-10 nmol; ICV; daily for 14 days) decreases cell proliferation in the dentate gyrus.

Products are for research use only. Not for human use.